
Sarecycline free base
CAS No. 1035654-66-0
Sarecycline free base ( —— )
产品货号. M23244 CAS No. 1035654-66-0
Sarecycline 游离碱是一种四环素衍生的窄谱抗生素。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
1G | ¥44348 | 有现货 |
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生物学信息
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产品名称Sarecycline free base
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Sarecycline 游离碱是一种四环素衍生的窄谱抗生素。
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产品描述Sarecycline free base is a tetracycline-derived, narrow-spectrum antibiotic.
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体外实验——
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体内实验Animal Model:Carrageenan-induced footpad edema male Sprague Dawley rats modelDosage:1 mg/kg, 5 mg/kg ,10 mg/kg, 25 mg/kg, 50 mg/kg, 75 mg/kg,100 mg/kg, 150 mg/kg Administration:Intraperitoneal injection (i.p.); Single dose. Before a subplantar injection of sterile 1 mg/0.1 mL carrageenan solution in the right hind paw.Result:Reduced inflammation to 55.7% and 53.1%, respectively, at doses of 75 mg/kg and 100 mg/kg compared to baseline.Animal Model:Carrageenan-induced footpad edema male Sprague Dawley rats model Dosage:0.33, 1, 3, or 9?mg/kg Administration:Intravenously Result:Achieved a 2-log10 reduction in the bacterial burden in the thigh at a dose comparable to that of doxycycline, with ED50s of 8.23 and 8.32?mg/kg, respectively.
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number1035654-66-0
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分子量487.5
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分子式C24H29N3O8
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (205.13 mM)
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SMILESCN(C)[C@@H]([C@H](C[C@H](Cc1c(CNCOC)ccc(O)c1C1=O)C1=C1O)[C@]11O)C(O)=C(C(N)=O)C1=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Pinazo A , Manresa M A , Marques A M , et al. Amino acid–based surfactants: New antimicrobial agents[J]. Advances in Colloid and Interface Science, 2016, 228:17-39.
产品手册




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